Human neuronal nicotinic acetylcholine receptor compositions...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07H 21/02 (2006.01) C07K 14/705 (2006.01) C12N 1/19 (2006.01) C12N 5/10 (2006.01) C12N 15/89 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2078572

Human neuronal nicotonic acetylcholine receptor subunits are described, as are methods for producing cells containing functional receptors employing such subunits. Also described are assay methods for determining the presence of functional HnAChRs in transfected cells, and for determining the agonist or antagonist activity of compounds with respect to such cells.

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