Human neutralizing monoclonal antibodies to human...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/13 (2006.01) A61K 39/42 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2195454

The present invention describes human monoclonal antibodies which immunoreact with and neutralize human immunodeficiency virus (HIV). Also disclosed are immunotherapeutic and diagnostic methods of using the monoclonal antibodies, as well as cell line for producing the monoclonal antibodies.

La présente invention se rapporte à des anticorps monoclonaux humains qui ont une immunoréaction avec le virus de l'immunodéficience humaine (VIH) et neutralisent celui-ci. L'invention se rapporte également à des procédés immunothérapeutiques et diagnostiques permettant d'utiliser ces anticorps monoclonaux ainsi qu'aux lignées cellulaires produisant ces anticorps monoclonaux.

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