Human neutralizing monoclonal antibodies to respiratory...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/13 (2006.01) A61K 39/42 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2144043

Human monoclonal antibodies and fragments thereof which bind and neutralize respiratory syncytial virus (RSV) antigenic subgroups A and B are disclosed. Also disclosed are diagnostic and immunotherapeutic methods of using the monoclonal antibodies as well as cell lines producing the monoclonal antibodies.

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