Human nim1 kinase

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/12 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 15/54 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2400238

The invention provides a nucleic acid molecule which encodes the human NIM1 kinase. It also provides for the use of the nucleic acid molecule, fragments, variants and complements thereof and of the protein, portions thereof and antibodies thereto for characterization, diagnosis, evaluation, treatment, or prevention of disorders associated with expression. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic organism or model system.

L'invention concerne une molécule d'acide nucléique qui code pour la kinase Nim1 humaine. L'invention porte également sur l'utilisation de ladite molécule d'acide nucléique, de fragments, de variantes et de compléments de celle-ci, et de la protéine, de parties de celle-ci et d'anticorps dirigés contre celle-ci, pour la caractérisation, le diagnostic, l'évaluation, le traitement ou la prévention de troubles associés à l'expression. L'invention se rapporte encore à des vecteurs d'expression et à des cellules hôtes pour la production de la protéine et d'un système d'organisme transgénique ou de modèle.

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