C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/08 (2006.01) A61K 38/04 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 5/08 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/40 (2006.01) C12N 9/02 (2006.01) G01N 33/564 (2006.01) G01N 33/576 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2111672
2111672 9222656 PCTABS00018 Human P450 IID6 cytochrome-derived peptide fragments, anti peptide anti fragment antibodies and applications thereof in the diagnosis of autoimmune hepatitis and more especially in the differential diagnosis between autoimmune hepatitis and other chronc viral forms of hepatitis, such as hepatitis C or B. Said human P450 cytochrome peptide fragment contains at least one P450 IID6 cytochrome immunodominant epitope and consists of an amino acid sequence comprising from 3 to 70 amino acids. Said peptide binds specifically with anti-LKM auto-antibodies produced in autoimmune hepatitis.
Borden Ladner Gervais Llp
Institut National de La Sante Et de La Recherche Medicale
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