Human papilloma virus vaccine formulations

Details Human papilloma virus vaccine formulations Human papilloma virus vaccine formulations

A - Human Necessities

61

K

A61K 39/12 (2006.01) A61K 47/00 (2006.01) A61P 31/20 (2006.01)

Patent

CA 2361837

New human papilloma virus (HPV) vaccine formulations exhibit enhanced long- term stability. Formulation components can include: virus-like particles (VLPs) absorbed onto aluminum, a salt, non-ionic surfactant, and a buffer. Additional formulations also contain a polymeric polyanionic stabilizer and a salt either in the presence or absence buffering agents and nonionic detergent.

L'invention concerne de nouvelles formulations vaccinales contre le virus du papillome humain (HPV), ces formulations présentant une stabilité à long terme améliorée. Les constituants de ces formulations peuvent notamment être: des particules d'aspect viral (VLP) absorbées sur de l'aluminium, un sel, un tensioactif non ionique, et un tampon. D'autres formulations renferment également un stabilisant polyanionique polymère et un sel, en présence ou en l'absence d'agents tampons et d'un détergent non ionique.

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