A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/12 (2006.01)
Patent
CA 2368391
Human Papillomavirus vaccine formulations which contain virus-like particles (VLPs) can be made more stable and have an enhanced shelf-life, by treating the VLPs to a disassembly and reassembly process. Also provided are formulation buffers to long term stable storage of VLPs.
L'invention porte sur des formulations de vaccin contre le papillomavirus qui contiennent des particules viro-induites pouvant être stabilisées et dont la durée de vie peut être améliorée en les traitant selon un procédé de désassemblage et réassemblage. L'invention porte également sur des tampons de formulation permettant un stockage à long terme des particules viro-induites.
Mach Henryk
Shi Li
Volkin David B.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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