Human pf4a receptors and their use

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/20 (2006.01) A61K 39/395 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 15/10 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2105998

cDNAs encoding a class of novel PF4ARs has been identified inhuman tissue. Provided herein are nucleic acid sequences of three PF4ARs (including the human IL-8 receptor) useful as a diagnostic and in the recombinant preparation of PF4ARs. The PF4ARs are used in the preparation and purification of antibodies capable of binding to the receptors, and in diagnostic assays.

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