C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 1/16 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2097935
2097935 9210756 PCTABS00013 The invention provides methods for detecting elevated levels of phospholipase A2, activating protein in persons suspected of having rheumatoid arthritis to thereby indicate the presence of rheumathoid arthritis in the person comprising the steps of providing a sample of body fluid or tissue from said person; contacting the sample with an antibody specific for phospholipase A2, activating protein such that the antibody binds with phospholipase A2, activating protein in the sample; detecting the antibody thereby indicating the presence of phospholipase A2 activating protein, whereby elevated levels of phospholipase A2 activating protein in the sample as compared with levels found in persons not having rheumatoid arthritis indicates the presence of rheumatoid arthritis in the person. Kits and reagents for detecting rheumatoid arthritis are also provided.
Bomalaski John S.
Clark Mike A.
Shorr Robert G. L.
Bomalaski John S.
Borden Ladner Gervais Llp
Clark Mike A.
Shorr Robert G. L.
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