C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
195/46, 195/78,
C07K 14/53 (2006.01) A61K 38/19 (2006.01) C12P 21/02 (2006.01) C12N 5/08 (2006.01)
Patent
CA 1340266
Highly purified pluripotent hematopoietic colony-stimulating factor (pluripotent CSF), a glycoprotein (MW 19,600) constitutively produced by human tumor cells has been highly purified from low serum-containing conditioned medium to apparent homogeneity. Pluripotent CSF supports the growth of human mixed colonies (CFU-GEMM), granulocyte-macrophage colonies (CFU-GM), early erythroid colonies (BFU-E) and induces differentiation of human leukemic cells. The specific activity of the purified pluripotent CSF in the CFU-GM assay is 1.5 X 10 8 U/mg protein.
505397
Gabrilove Janice L.
Mertelsmann Roland
Moore Malcolm A.s.
Platzer Erich
Welte Karl
Gabrilove Janice L.
Mertelsmann Roland
Moore Malcolm A.s.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Platzer Erich
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