Human preproinsulin-like growth factor i

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

530/7.1, 195/1.2

C12N 15/18 (2006.01) A61K 38/30 (2006.01) C07K 14/65 (2006.01)

Patent

CA 1340455

The invention provides DNA sequences encoding a human preproinsulin-like growth factor I protein and novel extension peptides. A novel preproinsulin-like growth factor I protein and novel extension peptides are also provided. The present invention further provides a human IGF-I gene which has been sequenced and which encodes at least two preproinsulin-like growth factor-I proteins. Various genes and DNA sequences useful in producing essentially pure mature IGF-I, preproinsulin-like growth factor I proteins and IGF-I gene related proteins are also provided.

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