C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/1.14, 195/1.
C12N 1/20 (2006.01) C07K 14/62 (2006.01) C12N 15/00 (2006.01) C12P 21/04 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1180289
Abstract of the Disclosure A DNA having a base sequence coding for human proinsulin and a DNA having a base sequence coding for human pre-proinsulin have been cloned, and novel recombinant DNA transfer vectors containing said cloned DNAs have been constructed. Novel microorganisms transformed by said recombinant transfer vectors have been obtained. Certain or said transformed microorganisms have demonstrated capability, to express,the cloned DNAs, synthesizing a protein comprising human proinsulin and a protein comprising human pre-proinsulin.
360565
Bell Graeme I.
Goodman Howard M.
Pictet Raymond
Rutter William J.
Sim & Mcburney
The Regents Of The University Of California
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