Human protein kinases and protein kinase-like enzymes

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) A61K 38/45 (2006.01) C07K 14/47 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 9/16 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2398430

The present invention relates to kinase polypeptides, nucleotides sequences encoding the kinase polypeptides, as well as various products and methods useful for the diagnosis and treatment jof various kinase-related diseases and conditions. Through the use of a bioinformatics strategy, mammalian members of the of PTK's and STK's have been identified and their protein structure predicted.

La présente invention concerne des polypeptides kinases, des séquences nucléotidiques codant pour les polypeptides kinases, ainsi que divers produits et méthodes utilisés dans le diagnostic et le traitement de diverses maladies et états pathologiques associés aux kinases. Grâce à l'utilisation d'une stratégie bioinformatique, des membres mammaliens des PTKs et des STKs ont été identifiés et leur structure protéique définie.

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