C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A61K 38/45 (2006.01) C07K 14/47 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 9/16 (2006.01) C12Q 1/48 (2006.01)
Patent
CA 2398430
The present invention relates to kinase polypeptides, nucleotides sequences encoding the kinase polypeptides, as well as various products and methods useful for the diagnosis and treatment jof various kinase-related diseases and conditions. Through the use of a bioinformatics strategy, mammalian members of the of PTK's and STK's have been identified and their protein structure predicted.
La présente invention concerne des polypeptides kinases, des séquences nucléotidiques codant pour les polypeptides kinases, ainsi que divers produits et méthodes utilisés dans le diagnostic et le traitement de diverses maladies et états pathologiques associés aux kinases. Grâce à l'utilisation d'une stratégie bioinformatique, des membres mammaliens des PTKs et des STKs ont été identifiés et leur structure protéique définie.
Manning Gerard
Martinez Ricardo
Plowman Gregory
Sudarsanam Sucha
Whyte David
Osler Hoskin & Harcourt Llp
Sugen Inc.
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