Human proteins and polynucleotides encoding them

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 38/20 (2006.01) A61K 39/395 (2006.01) A61K 49/00 (2006.01) C07K 14/47 (2006.01) C07K 14/54 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C12N 15/24 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2365910

The present invention provides novel isolated SECX polynucleotides and the membrane-associated or secreted polypeptides encoded by the SECX polynucleotides. Also provided are the antibodies that immunospecifically bind to a SECX polypeptide or any derivative, variant, mutant or fragment of the SECX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SECX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

L'invention concerne de nouveaux polynucléotides SECX isolés et les polypeptides associés à la membrane ou sécrétés codés par ces polynucléotides SECX. L'invention concerne également les anticorps qui se lient de manière immunospécifique à un polypeptide SECX ou à n'importe quel dérivé, variante, mutant ou fragment de ce polypeptide, polynucléotide ou anticorps SECX. L'invention concerne en outre des méthodes dans lesquelles le polypeptide, le polynucléotide et l'anticorps SECX servent à la détection et au traitement d'une grande variété de maladies, ainsi qu'à d'autres fins.

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