Human prourokinase variants, methods of producing same, dna...

Details Human prourokinase variants, methods of producing same, dna... Human prourokinase variants, methods of producing same, dna...

C - Chemistry, Metallurgy

12

N

195/39, 195/1.2,

C12N 15/58 (2006.01) C12N 1/00 (2006.01) C12N 9/72 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2017177

ABSTRACT OF THE DISCLOSURE A human prourokinase variant deficient in all or at least part of the first loop region or all or at least part of the third region of the epidermal growth factor (EGF) domain of human prourokinase, which shows a long blood half-life comparable to that of the whole EGF domain-deficient PUK variant.

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