Human rhinovirus receptor protein that inhibits virus...

A - Human Necessities – 61 – K

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167/103.9

A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339193

A water soluble human rhinovirus (HRV) major receptor preparation comprising detergent-complexed glycoprotein isolated from animal cells, preferably mammalian cells, that express the HRV major receptor and which exhibits the ability to bind to HRV capsids to substantially reduce infectivity of the virus. The purified, water soluble receptor is obtained by extracting cells expressing the receptor with detergent and isolating the solubilized detergent-glycoprotein complexes by binding to monoclonal antibody selective for the HRV receptor protein.

609473

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