Human rnase h and compositions and uses thereof

Details Human rnase h and compositions and uses thereof Human rnase h and compositions and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 9/22 (2006.01) C07H 21/04 (2006.01) C07K 16/40 (2006.01) C12N 15/52 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2312002

The present invention provides polynucleotides and polypeptides encoded thereby of human Type 2 RNase H. Methods of using these polynucleotides and polypeptides in enhancing antisense oligonucleotide therapies are also provided.

L'invention concerne des polynucléotides et des polypeptides codés par ceux-ci, du type humain 2 RNase H. Elle porte aussi sur des procédés d'utilisation de ces polynucléotides et de ces polypeptides dans l'amélioration de thérapies dans lesquelles des oligonucléotides antisens sont employés.

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