Human salty taste receptor and methods of modulating salty...

Details Human salty taste receptor and methods of modulating salty... Human salty taste receptor and methods of modulating salty...

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) C07K 17/02 (2006.01) C12Q 1/00 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2666962

Methods for identifying modulators of the epithelial sodium ion channel and for identifying modulators of salty taste perception are described. Also featured are isolated human salty taste receptors, artificial lipid bilayers comprising an epithelial sodium ion channels, and kits for practicing the claimed methods.

L'invention concerne des procédés destinés à identifier des modulateurs du canal sodique épithélial et des modulateurs du goût salé. L'invention concerne également des récepteurs humain du goût salé une fois isolés, des doubles couches lipidiques artificielles comprenant des canaux sodiques épithéliaux, ainsi que des kits permettant la mise en AEuvre des procédés revendiqués.

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