Human scf, a splice variant thereof, its pharmaceutical use

C - Chemistry – Metallurgy – 12 – N

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C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01)

Patent

CA 2203372

SCF which includes the following C-terminal sequence: Glu Ile Cys Ser Leu Leu Ile Gly Leu Thr Ala Tyr Lys Glu Leu Ser Leu Pro Lys Arg Lys Glu Thr Cys Arg Ala Ile Gln His Pro Arg Lys Asp or a C-terminal sequence which is substantially homologous thereto and its use in medicine, particularly in ensuring the correct development of pre- implantation embryos.

Le facteur des cellules souches comprend la séquence à extrémité C-terminale suivante: Glu Ile Cys Ser Leu Leu Ile Gly Leu Thr Ala Tyr Lys Glu Leu Ser Leu Pro Lys Arg Lys Glu Thr Cys Arg Ala Ile Gln His Pro Arg Lys Asp, ou une séquence à extrémité C-terminale sensiblement homologue à celle-ci et à son utilisation en médecine afin d'assurer notamment le développement correct d'embryons pré-implantés.

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