C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) A01K 67/00 (2006.01) C07H 21/04 (2006.01) C12N 5/02 (2006.01) C12N 9/00 (2006.01) C12N 9/90 (2006.01) C12N 15/63 (2006.01) C12Q 1/533 (2006.01)
Patent
CA 2405147
The present invention provides polynucleotides and polypeptides of a human serine racemase. The polynucleotides and polypeptides are used to further provide expression vectors, host cells comprising the vectors, probes and primers, antibodies against the serine racemase protein and polypeptides thereof, assays for the presence or expression of serine racemase and assays for the identification of compounds that interact with serine racemase and transgenic animals expressing human serine racemase.
L'invention concerne des polynucléotides et des polypeptides d'une sérine racémase humaine. Ces polynucléotides et ces polypeptides permettent d'obtenir des vecteurs d'expression, des cellules hôtes comprenant ces vecteurs, des sondes et des amorces, des anticorps contre la protéine de sérine racémase et ses polypeptides, des dosages permettant de déterminer la présence ou l'expression de sérine racémase et des dosages permettant d'identifier des composés qui interagissent avec la sérine racémase et des animaux transgéniques exprimant la sérine racémase humaine.
Connolly Thomas
Liu Yuan
Xia Menghang
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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