Human skin equivalents expressing exogenous polypeptides

Details Human skin equivalents expressing exogenous polypeptides Human skin equivalents expressing exogenous polypeptides

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 35/36 (2006.01) A61L 27/60 (2006.01) C12N 15/85 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2758178

The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.

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