Human sphingosine-1-phosphate phosphatase

Details Human sphingosine-1-phosphate phosphatase Human sphingosine-1-phosphate phosphatase

A - Human Necessities

01

K

A01K 67/00 (2006.01) A01K 67/033 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C07K 14/00 (2006.01) C07K 17/00 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 9/14 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01) C12P 21/04 (2006.01) C12Q 1/00 (2006.01) G01N 33/53 (2006.01) G01N 33/567 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2437577

The present invention provides polynucleotides and polypeptides of a human sphingosine-1-phosphate phosphatase, referred to herein as hSPP1. The polynucleotides and polypeptides are used to further provide expression vectors, host cells comprising the vectors, probes and primers, antibodies against the hSPP1 protein and polypeptides thereof, assays for the presence or expression of hSPP1 and assays for the identification of compounds that interact with hSPP1.

La présente invention concerne les polynucléotides et les polypeptides d'une sphingosine-1-phosphate phosphatase humaine, désignée ci-après par hSPP1. Les polynucléotides et polypeptides précités sont utilisés pour fournir des vecteurs d'expression, des cellules hôtes comprenant des vecteurs, sondes et amorces, des anticorps dirigés contre la protéine hSPP1 et les polylptides de cette dernière, des analyses permettant de détecter la présence ou l'expression de hSPP1 et des analyses permettant d'identifier des composés qui interagissent avec la hSPP1.

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