C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) C07H 21/04 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2117953
The polypeptides of the present invention are produced and secreted in pro-B cells and may be used for diseases relating to undergrown or abnormal proliferation of hematopoietic cells, neuronal enhancement or depression, immunological enhancement and depression, for example, inflammatory diseases (rheumatoid arthritis, ulcerative colitis, etc.), hematopoietic stemcytopenia after bone marrow transplantation, leukocytopenia, thrombocytopenia, B lymphopenia and T lymphopenia after chemotherapy, anemia, infectious diseases, cancer, leukocytosis, AIDS, neurodegenerative diseases (Alzheimer, multiple sclerosis, etc.), prevention or treatment of neuronal injury, prevention or treatment of disorder of bone metabolism (osteoporosis, etc.) or tissue repair. The DNA of the present invention may be utilized as an important and essential template in preparing the polypeptides of the present invention which are expected to be useful for diagnosis and treatment of gene diseases.
Honjo Tasuku
Shirozu Michio
Tada Hideaki
Ono Pharmaceutical Co. Ltd.
Riches Mckenzie & Herbert Llp
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