C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2362963
The present invention is directed to novel polypeptides having homology to a polypeptide suppressor of the Drosophila melanogaster fused protein and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
L'invention concerne des polypeptides présentant une homologie avec un suppresseur polypeptidique de protéine fusionnée de Drosophila melanogaster et avec des molécules d'acide nucléique codant ce type de polypeptide. L'invention concerne également des vecteurs et des cellules hôtes renfermant les séquences d'acide nucléique considérées, des molécules polypeptidiques chimères renfermant les polypeptides décrits que l'on fusionne à des séquences polypeptidiques hétérologues, des anticorps qui se lient aux polypeptides considérés et des procédés relatifs à l'élaboration de ces polypeptides.
de Sauvage Frederic J.
Gurney Austin L.
Murone Maximilien
Rosenthal Arnon
Stone Donna M.
Genentech Inc.
Smart & Biggar
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