Human t cell clone specific for rheumatoid arthritis

Details Human t cell clone specific for rheumatoid arthritis Human t cell clone specific for rheumatoid arthritis

C - Chemistry, Metallurgy

12

N

C12N 5/08 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2249023

A human T cell clone which recognizes the antigen expressed in the synovial cells of patients with rheumatoid arthritis (RA) as HLA-DR-restrictive and is useful for the elucidation of the mechanism of RA onset and the development of methods of treating and preventing RA.

Un clone de cellules T humaines reconnaissant l'antigène exprimé dans les cellules synoviales de patients atteints de polyarthrite rhumatoïde (PR) comme étant restreint par HLA-DR, est utile pour élucider le mécanisme de déclenchement de la polyarthrite rhumatoïde et pour l'élaboration de méthodes de traitement et de prévention de cette maladie.

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