C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/15 (2006.01) A61K 39/21 (2006.01) A61P 31/14 (2006.01) C07K 16/10 (2006.01) C12P 21/08 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2201419
Isolated and purified envelope protein of HTLV-I is provided devoid of non-envelope protein of HTLV-I and having substantially the same conformation as the envelope protein in native HTLV-I. The protein is produced recombinantly using a dual vaccinia/T7 polymerase system. Non-glycosylated and glycosylated forms of the protein are produced. Glycosylated forms are recognized by antibodies specific for the envelope protein of HTLV-I. Monoclonal antibodies are provided which are specific for the HTLV-I envelope protein and non-binding to HTLV-I envelope protein in denatured form. The HTLV-I envelope protein is cross-reactive with antibodies of HTLV-II and STLV. The envelope protein is useful in diagnosis of infection by HTLV-I and HTLV-II.
Arp Jacqueline
Dekaban Gregory A.
Foung Steven Kok Hing
Sim & Mcburney
Stanford University
University Of Western Ontario
LandOfFree
Human t-cell lymphotropic virus type i envelope protein and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human t-cell lymphotropic virus type i envelope protein and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human t-cell lymphotropic virus type i envelope protein and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2071132