Human thrombomodulin derivatives

Details Human thrombomodulin derivatives Human thrombomodulin derivatives

C - Chemistry, Metallurgy

12

N

530/13, 195/33.1

C12N 15/12 (2006.01) A61K 38/36 (2006.01) C07K 14/745 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2022713

X-7891A ABSTRACT OF THE DISCLSOURE Soluble human thrombomodulin derivatives comprise the N-terminal, epidermal growth factor homology and serine/threonine-rich regions of human thrombomodulin but lack the transmembrane and cytoplasmic domains of human thrombomodulin. Recombinant vectors and host cells for the production of these derivatives are provided.

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