Human tissue urokinase type plasminogen activator formulation

Details Human tissue urokinase type plasminogen activator formulation Human tissue urokinase type plasminogen activator formulation

A - Human Necessities

61

K

A61K 38/49 (2006.01) A61K 9/19 (2006.01) A61K 31/198 (2006.01) A61K 47/18 (2006.01) A61K 47/24 (2006.01) A61K 47/30 (2006.01) A61P 7/02 (2006.01) A61K 47/02 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2459120

This invention relates to an anhydrous arginine-free formulation including human tissue urokinase type plasminogen activator, lysine, phosphoric acid, and a non-ionic detergent, wherein the human tissue urokinase type plasminogen activator, lysine, phosphoric acid, and non-ionic detergent are in quantities of 10-60 mg, 100-700 mg, 20-100 mg, and 0.2-5 mg, respectively ; or in quantities of the same relative ratio.

L'invention concerne une formulation anhydre sans arginine comprenant un activateur de plasminogène de type urokinase de tissu humain, une lysine, un acide phosphorique et un détergent non ionique, l'activateur de plasminogène de type urokinase de tissu humain, la lysine, l'acide phosphorique et le détergent non ionique étant présents en quantités de 10 à 60 mg, de 100 à 700 mg, de 20 à 100 mg et de 0,2 à 5 mg, respectivement, ou des quantités du même rapport relatif.

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