Human tsc403 gene and human ing1l gene

Details Human tsc403 gene and human ing1l gene Human tsc403 gene and human ing1l gene

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2319668

This invention provides the TSC403 gene having a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:1, which is a novel gene of great utility particularly in the field of research, diagnosis, therapy, etc. for cancer of the lung, among other diseases. In addition, this invention provides the human ING1L gene comprising a nucleotide sequence coding for the amino acid sequence of SEQ ID NO: 4, which is a novel human gene useful for regulating the cell cycle, inhibiting or activating cell proliferation, studies on metabolic aging or apoptosis of cells, pathological exploration, diagnosis and therapy of cancer and other diseases, and screening for the development of new drugs.

L'invention concerne un nouveau gène TSC403 efficace dans différents domaines (étude, diagnostic, traitement, etc.), en particulier pour le cancer du poumon et autres maladies, qui renferme une séquence de base codant une séquence d'acides aminés numérotée SEQ ID N DEG :1. L'invention concerne également un nouveau gène humain utile dans la régulation et l'activation du cycle et de la prolifération cellulaires, l'étude du vieillissement cellulaire et de l'apoptose, la clarification de la pathologie de maladies comme le cancer, le diagnostic et le traitement des maladies de ce type, la mise au point et le criblage de nouveaux médicaments pour lesdites maladies, etc., qui renferme une séquence de base codant une séquence d'acides aminés numérotée SEQ ID N DEG :4.

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