Human ubiquitin carrier protein e2-like protein and cyclin...

Details Human ubiquitin carrier protein e2-like protein and cyclin... Human ubiquitin carrier protein e2-like protein and cyclin...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 38/16 (2006.01) A61P 31/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 9/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2292643

The invention provides two human proteins, involved in the cyclin-mediated regulatory pathway; a cyclin B-like protein, designated HCRP-2, and a ubiquitin conjugating enzyme E2-like protein, allegedly specifically involved in the degradation of mitotic cyclins, designated HCRP-1.

L'invention a trait à des protéines humaines liées aux cyclines (HCRP) et à des polynucléotides identifiant et codant pour HCRP. L'invention concerne également des vecteurs, des cellules hôtes, des agonistes, des anticorps et des antagonistes. L'invention se réfère également à des méthodes permettant de traiter des troubles associés à l'expression de HCRP.

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