C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 39/395 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2562953
The present invention concerns immunoglobulins, such as antibodies, which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and modulate the interaction between OSM and gp130. In typical embodiments, OSM is glycosylated. The invention also concerns antibodies that modulate the interaction between both Site II and Site III of OSM and their respective interacting partners. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
La présente invention concerne des immunoglobulines, telles que des anticorps qui se lient spécifiquement à l'oncostatine M (OSM), notamment l'OSM humaine (hOSM) et modulent l'interaction entre l'OSM et gp130. Dans des modes de réalisation typiques, l'OSM est glycosylé. L'invention concerne également des anticorps qui modulent l'interaction entre le site II et le site III de l'OSM et leurs partenaires d'interaction respectifs. L'invention concerne enfin des compositions pharmaceutiques, des procédés de dépistage et de traitement médical.
Ellis Jonathan Henry
Eon-Duval Alexandre
Germaschewski Volker
Plumpton Christopher
Rapson Nicholas Timothy
Glaxo Group Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Humanized and chimeric anti-osm antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Humanized and chimeric anti-osm antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Humanized and chimeric anti-osm antibodies will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2045682