Humanized anti-cd4 antibody with immunosuppressive properties

Details Humanized anti-cd4 antibody with immunosuppressive properties Humanized anti-cd4 antibody with immunosuppressive properties

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 37/04 (2006.01) A61P 37/06 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2519620

The invention relates to a humanized antibody derived from mouse monoclonal anti-CD4 antibody B-F5. Said antibody is able to activate CD25+CD4+ regulatory T cells and is useful for preparing immunosuppressive compositions.

Cette invention a trait à un anticorps humanisé dérivé d'un anticorps B-F5 anti-CD4. Cet anticorps, qui est capable d'activer des lymphocytes T régulateurs de CD25?+¿CD4?+¿, se révèle des plus utile en matière de préparation de compositions immunosuppressives.

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