Humanized anti-factor d antibodies and uses thereof

Details Humanized anti-factor d antibodies and uses thereof Humanized anti-factor d antibodies and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 16/36 (2006.01) A61P 27/02 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2667997

The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.

La présente invention concerne des anticorps monoclonaux humanisés antifacteurs D humain, leur séquences d'acides nucléiques et d'acides aminés, les cellules et vecteurs contenant ces anticorps et leur utilisation dans la préparation de compositions et de médicaments pour le traitement de maladies et de troubles associés à l'activation de compléments non contrôlée. Ces anticorps sont utiles pour le diagnostic, la prévention et le traitement de maladie.

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