Humanized anti-factor d antibodies and uses thereof

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/18 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2720853

The invention relates to anti-Factor D antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.

La présente invention concerne des anticorps anti-facteur D, leurs séquences dacide nucléique et dacides aminés, les cellules et vecteurs qui portent ces anticorps et leur production et leur utilisation dans la préparation de compositions et de médicaments pour le traitement de maladies et de troubles associés à une activation du complément excessive ou incontrôlée. Ces anticorps sont utiles pour le diagnostic, la prophylaxie et le traitement dune maladie.

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