Humanized anti-granulocyte mn-3 antibody and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/13 (2006.01) A61K 31/203 (2006.01) A61K 33/36 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 47/48 (2006.01) A61K 49/16 (2006.01) A61K 49/22 (2006.01) A61K 51/10 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C07K 16/46 (2006.01) C12N 5/10 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2500250

The present invention provides humanized, chimeric and human MN3 antibodies, fusion proteins, and fragments thereof. The antibodies, fusion proteins, and fragments thereof, as well as combinations with other suitable antibodies, are useful for the treatment and diagnosis of granulocyte related disorders and diseases, such as leukemia.

L'invention concerne des anticorps MN3 chimères et humains, des protéines de fusion et leurs fragments. Les anticorps, les protéines de fusion et leurs fragments, ainsi que des combinaisons avec d'autres anticorps appropriés sont utilisées pour le traitement et le diagnostic de troubles et de maladies associés aux granulocytes, tels que la leucémie.

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