C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01)
Patent
CA 2712220
The present invention relates to agents that are non-competitive antagonists of the CD94/NKG2A receptor such as certain anti-NKG2A antibodies, in particular humanized versions of murine anti-NKG2A antibody Z199, as well as methods of producing and using such agents and antibodies.
La présente invention porte sur des agents qui sont des antagonistes non compétitifs du récepteur CD94/NKG2A tels que certains anticorps anti-NKG2A, en particulier des versions humanisées de l'anticorps anti-NKG2A de souris Z199, ainsi que sur des procédés de production et d'utilisation de tels agents et de tels anticorps.
Chen Jianhe
Jing Su
Padkjaer Soeren Berg
Spee Petrus Johannes Louis
Yu Jiujiu
Dimock Stratton Llp
Novo Nordisk A/s
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