Humanized anti-il-6 antibodies

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/46 (2006.01) A01H 5/00 (2006.01) A01K 67/027 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2742786

The present invention relates to novel chimeric, humanized or CDR-grafted anti- IL-6 antibodies, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.

La présente invention concerne de nouveaux anticorps anti-IL-6 chimériques, humanisés ou à CDR greffé, comprenant des acides nucléiques isolés qui codent pour au moins un tel anticorps anti-IL-6, des vecteurs, des cellules hôtes, des animaux ou des plantes transgéniques, et des procédés de préparation et d'utilisation de ceux-ci, comprenant des compositions thérapeutiques, des procédés et des dispositifs.

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