Humanized antibodies against leukocyte adhesion molecule vla-4

Details Humanized antibodies against leukocyte adhesion molecule vla-4 Humanized antibodies against leukocyte adhesion molecule vla-4

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) G01N 33/567 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2182013

The invention provides humanized immunoglobulins that specifically bind to the VLA-4 ligand, and methods of treatment using the same. The methods are particularly useful for treatment of multiple sclerosis.

L'invention se rapporte à des immunoglobulines humanisées qui se fixent spécifiquement au ligand VLA-4, ainsi qu'à des procédés de traitement les utilisant. Ces procédés sont notamment utilisés dans le traitement de la sclérose en plaques.

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