C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) C07K 16/46 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2507080
The invention provides humanized antibodies that bind to a plurality of b- chemokines, particularly monocyte chemotactic proteins MCP-1, MCP-2 and MCP-3. The invention also provides therapeutic reagents and methods of treating disorders associated with detrimental MCP activity.
Cette invention concerne des anticorps humanisés qui se lient à une pluralité de chimiokines-b, en particulier aux protéines chimiotactiques de monocytes MCP-1, MCP-2 et MCP-3. Cette invention concerne également des réactifs thérapeutiques ainsi que des méthodes de traitement de troubles associés à l'activité néfaste des protéines chimiotactiques de monocytes.
de Fougerolles Antonin R.
Garber Ellen
Kotelianski Victor E.
Reid Carl
Saldanha Jose W.
Biogen Idec Ma Inc.
Gowling Lafleur Henderson Llp
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