Humanized antibodies against tl1a

Details Humanized antibodies against tl1a Humanized antibodies against tl1a

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2705292

Disclosed are humanized antibodies that bind specifically to TNF superfamily member 15 (TNFSF 15), also known as TL1A. Methods of making and using the anti-TL1 A antibodies are also described. The humanized antibodies may be antagonists and may used to treat or diagnose conditions associated with TL1A function.

L'invention concerne des anticorps humanisés se liant spécifiquement au membre 15 de la superfamille du TNF (TNFSF 15), également appelé TL1A. L'invention concerne encore des procédés de fabrication et des méthodes d'utilisation de ces anticorps anti-TL1A. Les anticorps humanisés selon l'invention peuvent être des antagonistes et peuvent servir dans le traitement ou le diagnostic d'affections associées à la fonction de TL1A.

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