C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 35/12 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 37/06 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2302752
The present invention is directed to humanized antibodies which bind human gp39 and their use as therapeutic agents. These humanized antibodies are especially useful for treatment of autoimmune diseases; and an immunosuppressant during transplantation of heterologous cells, tissues or organs, cell therapy, and gene therapy.
Cette invention concerne des anticorps humanisés qui se lient à gp39 humain ainsi que leur utilisation en tant qu'agents thérapeutiques. Ces anticorps humanisés sont plus particulièrement utiles pour traiter les maladies auto-immunes et servent d'immunosuppresseurs pendant la transplantation de cellules, de tissus ou d'organes hétérologues, pendant la cytothérapie et la thérapie génique.
Black Amelia
Hanna Nabil
Newman Roland A.
Padlan Eduardo A.
Biogen Idec Inc.
Idec Pharmaceuticals Corporation
Smart & Biggar
LandOfFree
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