C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/43 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01)
Patent
CA 2701790
The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies that specifically recognize and bind to specific epitopes from a range of ?-amyloid proteins. The antibodies of the present invention are particularly useful for the treatment of ocular diseases associated with pathological abnormalities/changes in the tissues of the visual system, particularly associated with amyloid-beta- related pathological abnormalities/changes in the tissues of the visual system.
La présente invention concerne de nouveaux procédés et de nouvelles compositions contenant des anticorps hautement spécifiques et hautement efficaces qui reconnaissent spécifiquement et se lient à des épitopes spécifiques d'une gamme de protéines ß-amyloïdes. Les anticorps de la présente invention se révèlent particulièrement utiles pour le traitement de maladies oculaires associées à des anomalies/modifications pathologiques dans les tissus du système visuel, en particulier associé à des anomalies/modifications pathologiques liées aux protéines amyloïdes Bêta dans les tissus du système visuel.
Muhs Andreas
Pfeifer Andrea
Pihlgren Maria
Watts Ryan
Ac Immune S.a.
Genentech Inc.
Goudreau Gage Dubuc
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