C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/10 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 16/00 (2006.01)
Patent
CA 2323787
A humanized antibody framework motif is described. Preferably, the motif is encoded by the VH gene of K5B8 and the VL gene of TR1.6. This humanized antibody preferably contains the variable region of a tat antibody.
La présente invention concerne le motif structural de la charpente d'un anticorps humanisé. Ce motif structural est codé de préférence par le gène V¿H? du K5B8 et le gène V¿L? du RT1.6. L'anticorps humanisé contient la région variable d'un anticorps tat.
Eberhardt Bridget
Lavecchio Joyce
Marasco Wayne
Mhashilkar Abner M.
Porter-Brooks Julie
Avant Immunotherapeutics Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Chiron Corporation
Dana Farber Cancer Institute Inc.
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