Hyaluronan-based imaging agents

Details Hyaluronan-based imaging agents Hyaluronan-based imaging agents

A - Human Necessities

61

B

A61B 5/055 (2006.01) A61K 49/00 (2006.01) A61K 49/18 (2006.01) C08B 37/08 (2006.01)

Patent

CA 2328698

Imaging agents containing hyaluronan (HA) and contrast agents. These imaging agents may include HA complexed with gadolinium, optionally with liposomes, and HA complexed with superparamagnetic iron oxides. A method of producing HA- based imaging agents includes mixing a solution of HA with a solution of contrast agent. A method of imaging using HA-based imaging agents includes using HA-based imaging agents to view cancer cells with magnetic resonance.

Agents d'imagerie contenant hyaluronan (HA) et des agents de contraste. Ces agents d'imagerie peuvent comprendre HA mis en complexe avec gadolinium, éventuellement avec des liposomes, ou HA mis en complexe avec des oxydes de fer supraparamagnétiques. Procédé servant à préparer ces agents d'imagerie à base de HA et consistant à mélanger une solution de HA avec une solution d'agent de contraste. Procédé d'imagerie mettant en application des agents d'imagerie à base de HA et consistant à utiliser ces agents d'imagerie afin de visualiser des cellules cancéreuses par résonance magnétique.

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