Hyaluronan product and process for manufacturing thereof

A - Human Necessities – 61 – K

Patent

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A61K 31/728 (2006.01) C08B 37/08 (2006.01)

Patent

CA 2389870

This invention relates to a chemically unmodified hyaluronan product which has a high molecular weight of 9-25 million Daltons and a zero shear viscosity from 5 to 30 billion mPa s. This unique product is durable and at the same time viscoelastic, and perfectly compatible within the biocompatible materials, for instance, as a cartilage substitute and as an intervertebral disc. The invention also relates to a process for manufacturing of said product.

La présente invention concerne un hyaluronan non chimiquement modifié de poids moléculaire élevé compris entre 9 et 25 millions de Daltons et possédant une viscosité à cisaillement nul comprise entre 5 et 30 milliards de mPa.s. Ce produit unique est résistant et en même temps viscoélastique, et il est parfaitement compatible au sein des matériaux biocompatibles, par exemple, comme substitut de cartilage et comme disque intervertébral. L'invention concerne aussi un procédé de fabrication de ce produit.

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