Hyaluronan synthase gene and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) A61K 31/715 (2006.01) A61K 31/728 (2006.01) A61K 39/102 (2006.01) A61P 31/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/79 (2006.01) C12P 19/04 (2006.01) C12P 21/00 (2006.01) C12Q 1/04 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2307842

The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active Streptococcus equisimilis hyaluronate synthase (seHAS), and to the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyaluronate is also known as hyaluronic acid or hyaluronan.

La présente invention concerne un segment d'acide nucléique dont un segment de la zone de codage code la synthase de l'hyaluronate de Streptococcus equisimilis, active du point de vue enzymatique. L'invention a aussi pour objet l'utilisation de ce segment d'acide nucléique dans la préparation des cellules de recombinaison à l'origine de la synthase de l'hyaluronate et de son produit d'acide hyaluronique. L'hyaluronate est également connu sous le nom d'acide hyaluronique ou d'hyaluronane.

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