Hyaluronate modified polymeric articles

Details Hyaluronate modified polymeric articles Hyaluronate modified polymeric articles

A - Human Necessities

61

L

400/1354, 117/16

A61L 27/00 (2006.01) A61L 27/16 (2006.01) A61L 27/18 (2006.01) A61L 27/54 (2006.01) C08F 8/00 (2006.01) C08L 75/04 (2006.01)

Patent

CA 1223383

ABSTRACT OF THE DISCLOSURE Polymeric materials (and articles made therefrom) including polyurethanes, polyesters, polyolefins, polyamides, polysiloxanes, vinylic and acrylic polymers are rendered bio- compatible by including with the polymeric material hyaluronic acid or a salt thereof. The hyaluronic acid may be coated onto the surface of the polymeric material dispersed through- out the body of the polymeric material, or both. The hyaluronic acid on the surface of the polymeric material may optionally be cross-linked. The biocompatible polymeric materials are used in the making of various prosthetic devices including heart valves, intraocular lenses, vascular grafts, pacemaker leads and the like.

461880

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