Hyaluronate modified polymeric articles

Details Hyaluronate modified polymeric articles Hyaluronate modified polymeric articles

C - Chemistry, Metallurgy

08

L

400/1300, 117/16

C08L 5/08 (2006.01) A61L 27/00 (2006.01) A61L 27/26 (2006.01) A61L 33/06 (2006.01) C08F 8/00 (2006.01) C08G 85/00 (2006.01) C08L 101/00 (2006.01)

Patent

CA 1218776

ABSTRACT OF THE DISCLOSURE Polymeric materials (and articles made therefrom) including polyurethanes, polyesters, polyolefins, polyamides, polysiloxanes, vinylic and acrylic polymers are rendered bio- compatible by including with the polymeric material hyaluronic acid or a salt thereof, The hyaluronic acid may be coated onto the surface of the polymeric material, dispersed through- out the body of the polymeric material, or both. The hyaluronic acid on the surface of the polymeric material may optionally be cross-linked. The biocompatible polymeric materials are used in the making of various prosthetic devices including heart valves, intraocular lenses, vascular grafts, pacemaker leads and the like.

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