Hyaluronidase inhibitor containing poly-gamma-glutamic acid...

A - Human Necessities – 61 – K

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Details

A61K 31/785 (2006.01) A61K 8/88 (2006.01) A61P 37/08 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2627454

The present invention relates to a hyaluronidase inhibitor containing poly- gamma- glutamic acid (PGA) as an active ingredient, a composition for maintaining skin elasticity and a composition for improving allergy, wherein each, of the compositions contains PGA as an active ingredient. The inventive compositions containing PGA are effective in maintaining skin moisturization and skin elasticity by effectively inhibiting the activity of hyaluronidase which is an enzyme that degrades hyaluronic acid present in the skin dermis. Also, the compositions can relieve allergic symptoms by inhibiting the permeability of inflammatory cells.

La présente invention concerne un inhibiteur de la hyaluronidase qui contient de l'acide poly-gamma-glutamique (PGA) en tant que matière active, une composition destinée au maintien de l'élasticité de la peau et une composition destinée à soulager l'allergie, chacune de ces compositions contenant du PGA en tant que matière active. Lesdites compositions contenant du PGA sont efficaces pour maintenir l'humidité et l'élasticité de la peau en inhibant efficacement l'activité de la hyaluronidase, enzyme qui dégrade l'acide hyaluronique présent dans le derme de la peau. Les compositions peuvent également soulager les symptômes allergiques en inhibant la perméabilité des cellules inflammatoires.

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