Hybrid cell line for producing complement-fixing monoclonal...

Details Hybrid cell line for producing complement-fixing monoclonal... Hybrid cell line for producing complement-fixing monoclonal...

A - Human Necessities

61

K

195/1.11

A61K 39/395 (2006.01) C07K 16/28 (2006.01) C12N 5/02 (2006.01) C12N 15/00 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1182406

ABSTRACT HYBRID CELL LINE FOR PRODUCING COMPLEMENT-FIXING MONOCLONAL ANTIBODY TO HUMAN T CELLS, ANTIBODY, AND METHODS Hybrid cell line for production of monoclonal antibody to an antigen found on all normal human T cells and cutaneous T lymphoma cells. The hybrid is formed by fusing splenocytes from immunized CAF1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

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